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Mature amygdala-mPFC connectivity following maternal deprivation. Unlike typically-raised (comparison) children who showed immature (positive) amygdala-medial prefrontal cortex (mPFC) connectivity, previously institutionalized (PI) children exhibited the mature pattern of negative amygdala-mPFC coupling, such that PI children resembled adolescents. SEM = standard error of the mean. (Copied from Gee et al. (in press). Proceedings of the National Academy of Sciences).
