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. 2014 Apr 21;13:59. doi: 10.1186/1475-2859-13-59

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Copyright © 2014 Feng et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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HPLC analysis and bioassay of nikkomycin Px and Pz. HPLC analysis of fermentation broth from S. ansochromogenes 7100 and its derivatives (A) and bioassays of nikkomycin production against C. albicans (B) and A. longipes (C). WT: S. ansochromogenes 7100, ΔsanL: sanL disruption mutant, sanLc: sanL complementary strain, NA: nicotinic acid, HBA: 4-hydroxybenzoic acid, isoNA: isonicotinic acid, X: nikkomycin X, Z: nikkomycin Z, Px:nikkomycin Px, Pz: nikkomycin Pz.