Table 1.
Summary of 1 H and 13 C NMR data for nikkomycin Px and Pz in D 2 O
| Position |
Nikkomycin Px |
Nikkomycin Pz |
||
|---|---|---|---|---|
| δ ( 1 H, mult., J ) | 13 C (δ) | δ ( 1 H, mult., J ) | 13 C (δ) | |
| 2 |
|
153.4 |
|
151.4 |
| 4 |
|
124.1 |
|
166.0 |
| 5 |
7.53 (1H, s) |
125.5 |
5.74 (1H, d, 8.1) |
102.4 |
| 6 |
9.16 (1H, s) |
180.3 |
7.42 (1H, d, 8.1) |
142.5 |
| 1´ |
5.53 (1H, d, 4.5) |
87.7 |
5.65 (1H, d, 4.2) |
91.2 |
| 2´ |
4.43 (1H, dd, 4.5, 5.5) |
72.3 |
4.29 (1H, dd, 4, 6) |
72.2 |
| 3´ |
4.52 (1H, t, 5.5) |
70.1 |
4.42 (1H, t, 6) |
69.8 |
| 4´ |
4.25 (1H, dd, 4.0, 5.5) |
82.3 |
4.17 (1H, dd, 3.5, 6.5) |
82.0 |
| 5´ |
4.74 (1H, d, 4.0) |
54.3 |
4.73 (1H, d, 4) |
54.3 |
| 6´ |
|
171.2 |
|
171.3 |
| 1´´ |
|
168.9 |
|
168.9 |
| 2´´ |
4.36 (1H, d, 4) |
57.0 |
4.35 (1H, d, 4) |
56.9 |
| 3´´ |
2.36 (1H, m) |
40.2 |
2.55 (1H, m) |
39.6 |
| 4´´ |
5.37 (1H, s) |
71.3 |
5.36 (1H, s) |
71.3 |
| 5´´ |
0.68 (3H, d, 7) |
5.11 |
0.67 (1H, d, 7.1) |
5.05 |
| 2´´´ |
8.7 (1H, s) |
138.5 |
8.68 (1H, s) |
138.6 |
| 3´´´ |
|
142.8 |
|
142.7 |
| 4´´´ |
8.49 (1H, d, 8.2) |
144.4 |
8.46 (1H, d, 8.2) |
144.3 |
| 5´´´ |
7.97 (1H, dd, 8.1, 6) |
127.1 |
7.94 (1H, dd, 8.1, 5.9) |
127.1 |
| 6´´´ | 8.62 (1H, d, 5.5) | 140.3 | 8.60 (1H, d, 5.7) | 140.3 |