Table 1.
Gene change comparing EA promoting group with control group
| Signal pathway | Gene | Sites | EA/control (Fold change) | EA/control (Fold up- or down-regulation) |
|---|---|---|---|---|
| MAPK |
MAPK6 (ERK3) |
D02 |
2.39 |
2.39 |
| MAPK |
MAPK13 |
D10 |
2.86 |
2.86 |
| PKC |
IL1R1 |
F08 |
2.18 |
2.18 |
| PKC |
PRKCA |
G01 |
2.40 |
2.40 |
| PKC |
PTGS2 |
G02 |
2.72 |
2.72 |
| PKC | IL1R2 | F09 | 0.26 | -3.85 |
Fold-change (2-ΔΔCt) is the normalized gene expression (2-ΔCt) in the test sample divided by the normalized gene expression (2-ΔCt) in the control sample. Fold-regulation represents the fold-change results in a biologically meaningful way. Fold-change values greater than one indicate a positive- or up-regulation, and the fold-regulation is equal to the fold-change. Fold-change values less than one indicate a negative or down-regulation, and the fold-regulation is the negative inverse of the fold-change.