Table 4.
Gene change comparing EA inhibitory group with non-acupoint group
| Signal pathway | Gene | Sites | EA/Non-acupoint (Fold change) | EA/Non-acupoint (Fold up- or down-regulation) |
|---|---|---|---|---|
| MAPK |
MAPK6 (ERK3) |
D02 |
0.18 |
-5.67 |
| MAPK |
MAPK10 (JNK3) |
D07 |
0.42 |
-2.40 |
| MAPK |
MAPK11 (p38bMAPK) |
D08 |
0.39 |
-2.58 |
| MAPK |
MAPK13 |
D10 |
0.28 |
-3.58 |
| MAPK |
MAPK3 (ERK1) |
G11 |
0.26 |
-3.83 |
| MAPK |
MAPK14 (p38MAPK) |
D11 |
0.47 |
-2.13 |
| PKC |
FGF2 |
F07 |
0.37 |
-2.67 |
| PKC |
IL1R1 |
F08 |
0.30 |
-3.31 |
| PKC |
IL1R2 |
F09 |
0.36 |
-2.81 |
| PKC |
MMP9 |
F11 |
0.22 |
-4.48 |
| PKC |
MYC |
F12 |
0.39 |
-2.59 |
| PKC |
PRKCA |
G01 |
0.23 |
-4.27 |
| PKC |
PTGS2 |
G02 |
0.19 |
-5.36 |
| PKC | COL1A1 | F05 | 4.81 | 4.81 |
Fold-change (2-ΔΔCt) is the normalized gene expression (2-ΔCt) in the test sample divided by the normalized gene expression (2-ΔCt) in the control sample. Fold-regulation represents the fold-change results in a biologically meaningful way. Fold-change values greater than one indicate a positive- or up-regulation, and the fold-regulation is equal to the fold-change. Fold-change values less than one indicate a negative or down-regulation, and the fold-regulation is the negative inverse of the fold-change.