Table 3.
Prevalence (with 95% confidence intervals) of respiratory symptoms at baseline in total baseline population, population at 10-yrs follow-up and population at 20-yrs follow-up, and differences between these groups given as ratios of baseline symptom prevalence (with bootstrapped 95% confidence intervals) in population at 10-yrs follow-up over total baseline population, and in population at 20-yrs follow-up over total baseline populationa
| Baseline population (95%CI) | 10-yrs follow-up population (95%CI) | Ratio of prevalences (95%CI) b | 20-yrs follow-up population (95%CI) | Ratio of prevalences (95%CI) b | ||
|---|---|---|---|---|---|---|
| Wheeze |
RHINE |
22.2% (20.4, 21.6) |
21.5% (19.9, 21.3) |
0.97 (0.95, 0.99) |
20.5% (19.0, 20.6) |
0.92 (0.90, 0.95) |
| |
Italian ECRHS |
10.0% (9.0, 10.5) |
10.2% (8.9, 10.8) |
1.02 (0.96, 1.07) |
10.1% (8.0, 11.2) |
1.01 (0.87, 1.14) |
| |
ISAYA |
15.1% (12.4, 14.6) |
13.7% (11.1, 13.8) |
0.91 (0.84, 0.98) |
- |
- |
| Asthma |
RHINE |
4.7% (4.3, 5.0) |
4.8% (4.4, 5.2) |
1.02 (0.99, 1.05) |
4.6% (4.3, 5.1) |
0.98 (0.92, 1.03) |
| |
Italian ECRHS |
4.2% (3.6, 4.6) |
4.2% (3.5, 4.7) |
1.00 (0.91, 1.09) |
3.8% (2.5, 4.5) |
0.90 (0.67, 1.10) |
| |
ISAYA |
5.3% (4.4, 5.8) |
5.0% (3.8, 5.6) |
0.94 (0.83, 1.07) |
- |
- |
| Rhinitis |
RHINE |
19.3% (19.3, 20.5) |
19.8% (19.7, 21.1) |
1.03 (1.01, 1.04) |
19.9% (19.9, 21.5) |
1.03 (1.00, 1.06) |
| |
Italian ECRHS |
15.9% (14.8, 16.6) |
15.8% (14.4, 16.7) |
0.99 (0.95, 1.03) |
18.2% (15.8, 20.0) |
1.14 (1.02, 1.26) |
| ISAYA | 20.7% (19.3, 21.8) | 21.1% (19.3, 22.7) | 1.02 (0.96, 1.08) | - | - |
aTotal baseline population: participants in 1989–92 in RHINE, 1991–93 in Italian ECRHS, 1998–2000 in ISAYA. 10-yrs follow up population: participants in 1999-2000 in RHINE and 1998–2000 in Italian ECRHS, 2008–09 in ISAYA. 20-yrs follow-up population: participants in 2010-12 in RHINE, 2008–09 in Italian ECRHS.
bCorrected for inter-dependency between long-term participants and total baseline participants, by using a non-parametric bootstrap method. Significant differences between long-term participants and all baseline participants are marked in bold font.