Table 6.
Baseline population OR (95%CI) | 10-yrs follow-up population OR (95%CI) | Ratio of ORs (95%CI) b | ||
---|---|---|---|---|
Ex-smokers |
RHINE |
1.05 (0.89, 1.22) |
1.09 (0.91, 1.31) |
1.04 (0.95, 1.14) |
|
Italian ECRHS |
1.69 (1.01, 2.83) |
1.93 (1.11, 3.36) |
1.14 (0.94, 1.42) |
|
ISAYA |
1.35 (0.94, 1.95) |
1.47 (0.90, 2.40) |
1.09 (0.75, 1.47) |
Current smokers |
RHINE |
1.08 (0.92, 1.25) |
1.02 (0.84, 1.24) |
0.94 (0.84, 1.07) |
|
Italian ECRHS |
0.72 (0.40, 1.31) |
0.67 (0.33, 1.36) |
0.93 (0.60, 1.31) |
|
ISAYA |
0.94 (0.68, 1.28) |
0.71 (0.44, 1.15) |
0.76 (0.51, 1.07) |
1-10 pack years |
RHINE |
1.04 (0.89, 1.21) |
1.11 (0.93, 1.34) |
1.07 (0.97, 1.18) |
|
Italian ECRHS |
1.35 (0.80, 2.30) |
1.59 (0.89, 2.84) |
1.18 (0.91, 1.50) |
|
ISAYA |
1.18 (0.88, 1.60) |
1.09 (0.72, 1.67) |
0.92 (0.67, 1.22) |
10-20 pack years |
RHINE |
1.04 (0.84, 1.30) |
1.07 (0.82, 1.40) |
1.03 (0.88, 1.18) |
|
Italian ECRHS |
0.77 (0.35, 1.68) |
0.72 (0.29, 1.76) |
0.94 (0.48, 1.35) |
|
ISAYA |
0.91 (0.56, 1.46) |
0.84 (0.41, 1.69) |
0.92 (0.49, 1.49) |
20+ pack years |
RHINE |
1.19 (0.91, 1.56) |
1.05 (0.74, 1.48) |
0.88 (0.69, 1.08) |
|
Italian ECRHS |
0.68 (0.29, 1.61) |
0.58 (0.21, 1.57) |
0.85 (0.41, 1.26) |
ISAYA | 0.71 (0.35, 1.47) | 0.45 (0.14, 1.50) | 0.63 (0.19, 1.43) |
aTotal baseline population: participants in 1999-2000 in RHINE and 1998–2000 in Italian ECRHS and ISAYA. 10-yrs follow-up population: participants in 2010–12 in RHINE, 2008–09 in Italian ECRHS and ISAYA. bCorrected for inter-dependency between long-term participants and total baseline participants, by using a non-parametric bootstrap method. Significant associations between risk factors and respiratory symptoms are marked in bold font, as well as significant differences between long-term participants and all baseline participants.