Table 3.
The allelic-wise analysis with a test for trend for the effect of MAPT rs242562 and GSK3B rs334558 on risk for PD
| Number of minor alleles | Cases | Controls | Crude OR (95% CI) | P value | Adjusted OR (95% CI)* | P* value |
|---|---|---|---|---|---|---|
| rs242562 |
|
|
|
|
|
|
| 0 |
36 |
64 |
1.000 |
|
1.000 |
|
| 1 |
116 |
107 |
1.927(1.186,3.132) |
0.008 |
1.892(1.154,3.102) |
0.011 |
| 2 |
56 |
60 |
1.659(0.960,2.868) |
0.070 |
1.628(0.931,2.846) |
0.087 |
| Test for trend |
|
|
1.262(0.964,1.651) |
0.091 |
1.250(0.950,1.646) |
0.111 |
| rs334558 |
|
|
|
|
|
|
| 0 |
74 |
97 |
1.000 |
|
1.000 |
|
| 1 |
112 |
136 |
1.079(0.729,1.598) |
0.702 |
1.051(0.704,1.570) |
0.807 |
| 2 |
25 |
29 |
1.130(0.611,2.089) |
0.697 |
1.091(0.583,2.039) |
0.785 |
| Test for trend | 1.068(0.806,1.415) | 0.647 | 1.047(0.785,1.395) | 0.756 |