Table 2.

Incidence and histopathological description of malignant and benign tumors induced by DMBA

	^WT (N = 28) N (%)*	^^Myr-Akt1 + (N = 28) N (%)*
Infiltrating poorly differentiated mammary carcinoma with bone metastases	0	2 (7.1%)
Poorly differentiated mammary carcinoma with necrosis	2 (7.1%)	7 (25.0%)
Salivary gland carcinoma with bone metastasis	1 (3.6%)	0
Carcinoma in the wall of the stomach	1 (3.6%)	1 (3.6%)
Carcinoid pattern of malignancy in lung	1 (3.6%)	0
Benign lesions of mammary gland with lymploid tissue	0	3 (10.7%)
Endometrial cystic changes with focal hyperplasia	1 (3.6%)	0
Benign squamous epithelium tumor	1 (3.6%)	1 (3.6%)

^Wild-type mice.

^^MMTV-myr-Akt1 transgenic mice.

*The percentages correspond to the total number of treated mice.