Table 1.
Demographics
|
2006/2007 Complete cohort |
2006/2007 Data for subjects studied in 2012 |
2012 Data |
|||
---|---|---|---|---|---|---|
Healthy smokers (N = 23) | COPD smokers (N = 24) | Healthy smokers (N = 11) | COPD smokers (N = 13) | Healthy smokers (N = 11) | COPD smokers (N = 13) | |
Female/male |
6/17 |
6/18 |
4/7 |
4/9 |
4/7 |
4/9 |
Age [years]a |
54 (42, 65) |
54 (46, 68) |
56 (51, 61) |
53 (50, 56) |
60 (56, 66) |
58 (55, 61) |
BMI [kg/m2] |
25.4 ± 2.5 |
25.3 ± 3.4 |
25.5 ± 1.8 |
24.4 ± 3.0 |
26.7 ± 3.0 |
25.5 ± 3.9 |
Pack-years & |
34.0 (21.0) |
48.0 (15.5)*** |
32.0 (21.0) |
47.0 (15.0) |
37.5 (16.8) |
50.1 (16.7) |
Cotinine (ng/mL) |
1262 ± 722 |
1561 ± 968 |
1232 ± 548 |
1620 ± 748 |
867 ± 659 |
1585 ± 678 |
FEV1 [L] |
3.8 ± 0.8 |
2.0 ± 0.3*** |
3.5 ± 0.6 |
2.0 ± 0.3 |
3.2 ± 0.5 |
1.5 ± 0.5 |
FEV1 % pred. |
112.5 ± 14.1 |
60.5 ± 6.8*** |
114.9 ± 12.8 |
60.7 ± 5.5 |
109,6 ± 14.2 |
47.3 ± 15.0 |
FVC [L] |
5.1 ± 1.0 |
4.2 ± 0.9** |
4.7 ± 0.9 |
4.3 ± 0.8 |
4.5 ± 0.7 |
3.6 ± 0.8 |
FEV1/FVC [%] |
75.4 ± 5.0 |
48.7 ± 7.4*** |
74.3 ± 5.1 |
48.2 ± 6.7 |
71.1 ± 4.2 |
41.0 ±11.7 |
pO2 [mm Hg] | 82.9 ± 9.7 | 73.3 ± 5.3*** | 81.2 ± 9.2 | 75.1 ± 5.7 | 76.5 ± 7.4 | 69,2 ± 7.6 |
In 2012: COPD smokers: 2 quit smoking, 2 reduced smoking; healthy smokers: 2 quit smoking, 1 reduced smoking.
a:presented as mean (minimum, maximum), all other data is presented as mean ± SD, ** = p < 0.01, *** = p < 0.005 & median (IQR).