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Schematic diagram of the co-expression cassette of Fab(H+L) in pPKStrastFabHL. The Fab(H+L) expression plasmid pPKStrastFabHL was constructed as described in Methods. The HC and LC genes of the anti-HER2 Fab fragment (shaded bars) fused with the signal peptide of CspA from C. ammoniagenes (open bars) were expressed under control of the cspB promoter from C. glutamicum (thick arrows).
