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. 2014 Apr 18;14:37. doi: 10.1186/1472-6823-14-37

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Copyright © 2014 Sinclair et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Changes in efficacy parameters (LOCF). (A) Change in HbA_1c, (B) change in FPG, (C) percent change in body weight, (D) change in systolic BP, and (E) change in diastolic BP. LOCF, last observation carried forward; FPG, fasting plasma glucose; BP, blood pressure; LS, least squares; SE, standard error; CI, confidence interval; PBO, placebo; CANA, canagliflozin.