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. 2014 Jun;28(6):2538–2550. doi: 10.1096/fj.13-247221

Figure 4.

Figure 4.

Haplotype structure of Chrm2 and the association with susceptibility to hyperoxia-induced neutrophilia in BALF in inbred neonatal mice. A) Truncated haplotype structure of Chrm2 with synonymous (Cs) and nonsynonymous (Cn) coding SNPs in strains of mice with similar haplotype. Uppercase symbols represent validated nucleotides. Lowercase symbols represent imputed nucleotides. B) Mean number of PMNs in strains of mice with the Chrm2 haplotypes 1 (CCT; n=3 strains), 2 (GCC; n=17 strains), and 3 (CTT; n=14 strains). *P < 0.05, Student-Newman-Keuls test. C) Mean number of BALF PMNs for strains (n=21) homozygous for the rs30378838 C allele and strains (n=15) homozygous for the T allele. *P < 0.05; t test.