Table 2.
Mycolactone detection by mass spectrometry and cytotoxicity assay in patients with M. ulcerans disease sampled for M. ulcerans culture
|
Time |
Week 0 |
Week 6 |
Week 12 |
|||
|---|---|---|---|---|---|---|
| Mycolactone detection |
Culture result |
Culture result |
Culture result |
|||
| Positive | Negative | Positive | Negative | Positive | Negative | |
| Cytotoxicity positive |
35 |
17 |
7 |
7 |
2 |
0 |
| Cytotoxicity negative |
5 |
3 |
0 |
1 |
0 |
1 |
| Total (1) |
40 |
20 |
7 |
8 |
2 |
1 |
| MS positive |
26 |
16 |
6 |
7 |
0 |
0 |
| MS negative |
14 |
4 |
0 |
1 |
2 |
1 |
| Total (2) | 40 | 20 | 6 | 8 | 2 | 1 |
MS - Mass spectrometry. Total (1) represents sub-total of comparison of mycolactone detection by cytotoxicity and culture results. Total (2) represents sub-total of comparison of mycolactone detection by mass spectrometry and culture results.