Table 5. Number of patients identified correctly and incorrectly as bearing insignificant PC and therefore being eligible for active surveillance.
Tosoian | Adamy | Van den Bergh | Whitson | Soloway | Selvadurai | D'Amico | Entire cohort | |
---|---|---|---|---|---|---|---|---|
Insignificant cancer, classical definition | ||||||||
Correctly eligible for AS | 3 | 9 | 3 | 9 | 8 | 12 | 9 | 20 |
Incorrectly eligible for AS | 41 | 137 | 60 | 160 | 98 | 294 | 197 | 396 |
Total eligible for AS | 44 | 146 | 63 | 169 | 106 | 306 | 206 | 415 |
Percent of eligible patients correctly identified as insignificant PC |
7 |
6 |
5 |
5 |
8 |
4 |
4 |
5 |
Insignificant cancer, ERSPC definition | ||||||||
Correctly eligible for AS | 17 | 45 | 22 | 47 | 36 | 66 | 51 | 99 |
Incorrectly eligible for AS | 27 | 101 | 41 | 122 | 70 | 240 | 155 | 316 |
Total eligible for AS | 44 | 146 | 63 | 169 | 106 | 306 | 206 | 415 |
Percent of eligible patients correctly identified as insignificant PC |
39 |
31 |
35 |
28 |
34 |
22 |
25 |
24 |
Organ-confined low-grade cancer | ||||||||
Correctly eligible for AS | 28 | 81 | 39 | 88 | 57 | 134 | 97 | 181 |
Incorrectly eligible for AS | 16 | 65 | 24 | 81 | 49 | 172 | 109 | 234 |
Total eligible for AS | 44 | 146 | 63 | 169 | 106 | 306 | 206 | 415 |
Percent of eligible patients correctly identified as insignificant PC | 64 | 55 | 62 | 52 | 54 | 44 | 47 | 44 |
Abbreviations: AS=active surveillance; AUC=area under the receiver operator characteristic curve; ERSPC=European Randomised Study of screening for prostate cancer; PC=prostate cancer.