Table 6. Comparison of accuracy of tools in unscreened UK and screened USA data sets.
|
Insignificant cancer, classical definition |
Insignificant cancer, ERSPC definition |
Organ-confined low-grade cancer |
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| |
This study |
Iremashvili et al, 2012 |
This study |
Iremashvili et al, 2012 |
This study |
Iremashvili et al, 2012 |
||||||
| Approach | AUC | 95% confidence interval | AUC | 95% confidence interval | AUC | 95% confidence interval | AUC | 95% confidence interval | AUC | 95% confidence interval | AUC | 95% confidence interval |
| Tosoian |
0.53 |
0.44–0.62 |
0.63 |
0.59–0.68 |
0.54 |
0.50–0.59 |
0.6 |
0.56–0.63 |
0.54 |
0.51–0.58 |
0.59 |
0.54–0.63 |
| Adamy |
0.58 |
0.45–0.70 |
0.63 |
0.58–0.67 |
0.57 |
0.51–0.63 |
0.62 |
0.57–0.67 |
0.59 |
0.54–0.63 |
0.59 |
0.54–0.64 |
| Van den Bergh |
0.51 |
0.42–0.60 |
0.68 |
0.63–0.72 |
0.55 |
0.50–0.59 |
0.64 |
0.60–0.69 |
0.56 |
0.52–0.59 |
0.62 |
0.57–0.67 |
| Whitson |
0.55 |
0.43–0.67 |
0.61 |
0.57–0.65 |
0.55 |
0.49–0.60 |
0.59 |
0.55–0.64 |
0.57 |
0.52–0.62 |
0.56 |
0.51–0.61 |
| Soloway |
0.6 |
0.48–0.72 |
0.68 |
0.64–0.73 |
0.57 |
0.52–0.63 |
0.63 |
0.58–0.67 |
0.55 |
0.51–0.60 |
0.6 |
0.55–0.65 |
| Any criteria |
0.42 |
0.30–0.53 |
0.61 |
0.57-0.65 |
0.45 |
0.40–0.50 |
0.58 |
0.54–0.63 |
0.5 |
0.46–0.53 |
0.55 |
0.50–0.60 |
| All criteria | 0.53 | 0.44–0.62 | 0.63 | 0.59–0.68 | 0.54 | 0.50–0.58 | 0.6 | 0.56–0.64 | 0.54 | 0.51–0.57 | 0.58 | 0.54–0.62 |
Abbreviations: AUC=area under the receiver operator characteristic curve; ERSPC=European Randomised Study of screening for prostate cancer.