Table 2.
Changes in period and cohort effects on haematological cancer mortality rates by sex, Spain 1952-2006
| |
Net drift
1
|
Change in period effect
2
|
Change in cohort effect
3
|
||||
|---|---|---|---|---|---|---|---|
| Haematological cancer |
Year of death |
Difference in |
Birth year |
Difference in |
Birth year |
Difference in |
|
| (95% CI) | (95% CI) | APC (95% CI) | (95% CI) | APC (95% CI) | (95% CI) | APC (95% CI) | |
|
Hodgkin’s disease |
|
|
|
|
|
|
|
| Men |
-2.3 (-2.6 to -2.1) |
1967.7 (1965.5–1972.5) |
-6.3 (-7.5 to -5.0) |
1914.1 (1904.0–1919.0) |
-2.3 (-2.9 to -1.7) |
— |
— |
| Women |
-1.8 (-2.0 to -1.5) |
1965.9 (1965.0–1968.0) |
-5.2 (-6.0 to -4.4) |
1915.1 (1909.5–1919.0) |
-3.5 (-4.8 to -2.2) |
1932.0 (1927.0–1976.5) |
1.5 (0.2 to 2.9) |
|
Non-Hodgkin’s lymphoma |
|
|
|
|
|
|
|
| Men |
2.3 (2.0 to 2.5) |
1994.5 (1990.0–NA) |
-3.3 (-5.1 to -1.5) |
1919.9 (1915.0–1924.5) |
-3.6 (-4.1 to -3.1) |
1968.7 (1962.0–1975.0) |
-4.9 (-6.2 to -3.6) |
| Women |
3.0 (2.7 to 3.3) |
1994.5 (1989.0–NA) |
-3.5 (-6.0 to -1.0) |
1918.7 (1917.0–1920.5) |
-4.3 (-4.6 to -3.9) |
1954.1 (1945.5–1962.0) |
-2.3 (-2.9 to -1.6) |
|
Multiple myeloma |
|
|
|
|
|
|
|
| Men |
3.6 (3.4 to 3.9) |
1986.1 (1975.5–1994.0) |
-4.3 (-6.0 to -2.6) |
1909.1 (1905.0–1911.5) |
-6.1 (-6.9 to -5.2) |
1928.9 (1923.5–1936.5) |
-1.8 (-2.3 to -1.3) |
| Women |
3.6 (3.2 to 3.9) |
1987.0 (1975.0–1994.0) |
-3.9 (-5.7 to -2.0) |
1905.4 (1902.5–1910.0) |
-6.1 (-7.8 to -4.5) |
1924.7 (1922.0–1930.0) |
-2.9 (-3.5 to -2.3) |
|
Leukaemia |
|
|
|
|
|
|
|
| Men |
-0.1 (-0.2 to 0.1) |
1964.5 (NA–1969.5) |
-3.6 (-5.8 to -1.3) |
1913.4 (1907.5–1916.5) |
-4.3 (-4.9 to -3.7) |
1964.6 (1939.5–1973.0) |
-2.5 (-3.3 to -1.7) |
| Women | -0.3 (-0.5 to -0.2) | 1964.5 (NA–1967.0) | -4.4 (-5.7 to -3.0) | 1910.1 (1907.5–1915.5) | -5.1 (-5.8 to -4.4) | 1966.2 (1953.5–1972.5) | -2.8 (-3.6 to -2.0) |
1Overall annual percent change in age-adjusted mortality rates and 95% confidence interval (CI) obtained from the sum of period and cohort linear slopes from the three-factor model. 2Difference in annual percent changes (APCs) before and after the estimated year of death with significant trend change as obtained from the weighted joinpoint regression analysis of period curvatures from the three-factor model. 3Differences in annual percent changes (APCs) before and after the estimated birth years with significant trend changes as obtained from the weighted joinpoint regression analysis of cohort curvatures from the three-factor model.