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. Author manuscript; available in PMC: 2014 May 15.
Published in final edited form as: Pediatr Res. 2013 Feb 18;73(5):612–620. doi: 10.1038/pr.2013.38

Figure 4.

Figure 4

Effect of IUGR on RAR mRNA transcript levels in homogenates of rat lung tissue. Results are shown as mean ± SD for n=6/group. White fill indicates male control, black fill indicated male IUGR, grey fill indicates female control and hatched fill indicates female IUGR. Panel a: RARα mRNA level for male pups, left side and female pups, right side. Panel b: RARβ mRNA level for male pups, left side and female pups, right side. Panel c : RARγ mRNA level for male pups, left side and female pups, right side. IUGR resulted in age-specific differences in lung RAR mRNA transcript levels. IUGR had significant effects on mRNA transcript levels for RARα, β, and γ in male pups compared to age-matched control male pups at P0, P6, and P21. Similarly, IUGR had significant effects on mRNA transcript levels for RARα and γ in female pups compared to age-matched control female pups at P0, P6, and P21. On the other hand, IUGR did not cause sex-specific differences in lung RAR mRNA transcript levels.†Different from P0 (p<0.05). §Different from P6 (p<0.05). *Different from age and sex-matched IUGR (p<0.05). Nonparametric statistical tests were used (see Methods section).