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(a,b) Representative photomicrographs serially stained for hematoxylin and eosin, PMS2 and BRAFV600E of (a) DNA mismatch repair-proficient/BRAF wild-type colorectal carcinoma and (b) DNA mismatch repair-proficient/BRAFV600E mutant tumor (original magnifications, × 400). (c) Kaplan–Meier survival functions of the four immunohistochemistry phenotypes. (d) Univariate Cox regression survival function of the four immunohistochemistry phenoytpes.
