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. 2012 Oct 17;2012(10):CD010005. doi: 10.1002/14651858.CD010005.pub2

6. Regular salmeterol & ICS v ICS trial details.

  Duration (Weeks) Salmeterol & ICS ICS alone Dose of Fluticasone mcg/day Dose of Salmeterol mcg/day Combined Inhaler Age Ranges
Li 2010 12 173 177 200 100 4 to 11
Malone 2005 12 101 102 200 100 4 to 11
NCT01192178 16 171 168 200 100 4 to 11
SAM40012 24 181 181 200 100 4 to 11
SAS30021 12 304 304 100 50 4 to 11
Total mean = 15 weeks 930 932        
All trials were sponsored by GSK and contributed data on all‐cause mortality and non‐fatal serious adverse events