Lipoxin A4 / aspirin-triggered lipoxin |
Decreases adherence of leukocytes |
Papayianni et al. (71) |
Reduces vascular leakage |
Takano et al. (98) |
Lowers prostaglandin E2 levels in exudates |
Pouliot et al. (73) |
Reduces the number of apoptotic neutrophils |
Perretti et al. (72) |
Inhibits neutrophil recruitment |
Serhan et al. (90) |
Attenuates expression of the nuclear factor-kappaB gene |
Chiang et al. (20) |
Blocks leukocyte adhesion protein-1 and chemotaxis |
Ohira et al. (70) |
Promotes lymphatic removal of phagocytes |
Bannenberg et al. (13) |
Activates FLRP2/Lipoxin A4 receptor receptor internalization and phagocytosis |
Maderna et al. (59) |
Inhibits T-cell adhesion to vascular and salivary epithelium |
Chintamani et al. (21) |
Enhances microbial phagocytic function |
Tobin et al. (100) |
Resolvin E1 |
Inhibits neutrophil infiltration |
Serhan et al. (86) |
Modulates chemokine/cytokine synthesis |
Bannenberg et al. (13) |
Promotes healing of inflamed tissues and bone regeneration |
Hasturk et al. (39) |
Enhances phagocytosis |
Schwab et al. (80) |
Activates lymphatic removal of phagocytes |
Van Dyke et al. (101) |
Attenuates systemic production of C-reactive protein and interleukin-1 |
Hasturk et al. (38) |
Reduces eosinophil and lymphocyte recruitment |
Aoki et al. (5) |
Regulates adipokines |
Gonzalez-Periz et al. (35) |
Decreases inflammatory actions of cyclooxygenase-2 |
Li et al. (56) |
Attenuate expression of the nuclear factor-kappaB gene |
Ishida et al. (46) |
Lowers the number of monocytes |
Li et al. (56) |
Increases CD55 expression on epithelial cells and polymorphonuclear cell clearance |
Campbell et al. (18) |
Rescues impaired phagocytosis in LAP patient macrophages |
Freedman et al. (30) |
Prevents rejection of allograft |
Levy et al. (55) |
Activates anti-apoptotic signals |
El Kebir et al. (27) |
Resolvin D1 |
Inhibits neutrophil recruitment |
Serhan et al. (89) |
Anti-hyperalgesic properties |
Albert et al. (2) |
Shortens resolution interval |
Hong et al. (43) |
Reduces oxidative stress-mediated inflammation |
Spite et al. (97) |
Attenuates agonist pain molecules |
Bang et al. (12) |
Induces macrophage phagocytosis |
Krishnamoorthy et al. (52) |
Stimulates the M2 macrophage phenotype |
Titos et al. (99) |
Temporally regulates microRNAs |
Recchiuti et al. (75) |
Reduces cytokines in bronchoalveolar lavage fluid |
Wang et al. (105) |
Ameliorates insulin sensitivity |
Hellman et al. (40) |
Enhances microbial clearance |
Chiang et al. (19) |
Reduces levels of prostaglandins and leukotrienes |
Norling et al. (67) |
Protectin D1/AT-PD1 |
Decreases inflammatory actions of cyclooxygenase-2 |
Marcheselli et al. (63) |
Inhibits neutrophil infiltration |
Bannenberg et al. (13) |
Modulates chemokine/cytokine synthesis |
Serhan et al. (88) |
Regulates T-cell migration |
Ariel et al. (6) |
Regulates macrophage function |
Duffield et al. (25) |
Up-regulates CCR5 expression on apoptotic leukocytes |
Schwab et al. (80) |
Prevents hepatocyte steatosis |
Gonzalez-Periz et al. (35) |
Inhibits pain signals |
Bang et al. (12) |
Suppresses eosinophil chemotaxis and adhesion |
Miyata et al. (65) |
Maresin -1 |
Reduces neutrophil numbers in exudate |
Serhan et al. (93) |
Enhances macrophage phagocytic functions |
Serhan et al. (87) |
Decreases transendothelial polymorphonuclear cell migration |
Shinohara et al. (95) |