Table 3.
Mean yearly volume and costs of enzyme replacement therapy by disease state
| Disease state | N* | Number of vials | 95% LCL | 95% UCL | Costs | 95% UCL | 95% UCL |
|---|---|---|---|---|---|---|---|
| Signs/symptoms |
28 |
76 |
62 |
91 |
151,147 |
123,501 |
180,088 |
| Recovery |
19 |
63 |
49 |
75 |
124,183 |
97,529 |
149,041 |
| Splenectomy |
6 |
78 |
50 |
111 |
155,082 |
98,443 |
220,004 |
| Bone complication |
9 |
102 |
75 |
132 |
202,348 |
149,319 |
261,573 |
| Multiple complications |
18 |
86 |
70 |
102 |
170,317 |
138,201 |
202,653 |
| Malignancy | 5 | 130 | 68 | 209 | 257,469 | 135,582 | 414,084 |
LCL: lower limit of the confidence interval, UCL: upper limit of the confidence interval.
*Patients may contribute to more than one disease state.