Figure 2.

Crx and Aanat day/night expression in the adult rat pineal gland. Radiochemical in situ hybridization autoradiographs of midsagittal brain sections through the pineal gland of rats killed at daytime (Zeitgeber time 6) and nighttime (Zeitgeber time 18). Images are orientated with caudal to the left. Crx displays a specific expression in the pineal gland. Studies have shown a diurnal rhythm of Crx expression in the rat pineal gland with a night time peak [7, 35, 71]. Aanat also exhibits a pineal-specific expression; however, daytime transcript levels are very low. Scale bar, 1 mm. Methodological details have been previously published [14, 71].