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. 2014 Apr 16;7:34. doi: 10.1186/1756-8722-7-34

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Copyright © 2014 Wei et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Rituximab-associated survival benefits based on CD44H and CD44v6 expression status. The Kaplan-Meier method was used to estimate the OS and EFS distributions with the log-rank test performed to compare the survival curves. For cases that were either CD44H+ (A and B) or CD44H- (C and D), survival outcomes after CHOP and R-CHOP treatments were compared for OS (A and C) and EFS (B and D). CHOP versus R-CHOP comparison was also made for OS (E and G) and EFS (F and H) among the CD44V6+ (E and F) and CD44v6- (G and H) subgroups.