Table 3.
Blood pressure (BP), carotid blood flow (F), and carotid resistance (R) from control or diabetic rats.
| Rats | Cardiovascular parameters | ||
|---|---|---|---|
| BP (mmHg) | F (mL/min) | R (U) | |
| Nontreated control | 81.7 ± 5.4 | 6.11 ± 0.48 | 14.1 ± 2.3 |
| Nontreated diabetic | 99.2 ± 8.1 | 2.37 ± 0.21* | 44.6 ± 3.2* |
| DX600-treated control | 76.4 ± 6.2 | 2.09 ± 0.17* | 41.9 ± 3.5* |
| DX600-treated diabetic | 89.2 ± 7.5 | 2.13 ± 0.19 | 45.2 ± 4.2 |
| Angiotensin-(1–7)-treated control | 79.5 ± 6.1 | 5.76 ± 0.32 | 13.2 ± 2.9 |
| Angiotensin-(1–7)-treated diabetic | 97.0 ± 9.1 | 6.29 ± 0.51# | 15.0 ± 2.1# |
| A779-treated control | 81.1 ± 7.4 | 1.99 ± 0.14* | 40.2 ± 4.3* |
| A779-treated diabetic | 98.7 ± 8.3 | 2.44 ± 0.23 | 42.4 ± 4.1 |
| Angiotensin-(1–7) + A779-treated control | 75.6 ± 7.0 | 2.05 ± 0.19∗,† | 38.2 ± 3.8∗,† |
| Angiotensin-(1–7) + A779-treated diabetic | 99.5 ± 9.2 | 1.97 ± 0.11† | 46.3 ± 4.7† |
The values are significantly different (P < 0.01; n = 5) from nontreated control rats (∗), nontreated diabetic rats (#), or the respective rats treated with angiotensin-(1–7) (†).