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. Author manuscript; available in PMC: 2014 May 15.
Published in final edited form as: Biochim Biophys Acta. 2012 Aug 3;1824(11):1245–1253. doi: 10.1016/j.bbapap.2012.07.014

Figure 8.

Figure 8

Mechanism of action of TYW1. H-atom abstraction either by dAdo• or another radical generated by it from m1G substrate initiates the radical cascade. A conserved Lys residue is proposed to be involved in formation of Schiff base with pyruvate.