Table 1.
Clinical results of 1420 CCS cycles according to the origin of the oocytes and embryos.
| Fresh cycles | Mixed vitrified oocytes | Mixed day-2 vitrified embryos | Mixed day-3 vitrified embryos | |
|---|---|---|---|---|
| Number of cycles | 774 | 320 | 235 | 91 |
| Mean female age (SD) | 39.4 (3.2) | 39.7 (3.9) | 38.9 (3.5) | 38.3 (3.4) |
| Mean number of embryos analyzed (SD) | 4.7 (2.9)b,c | 5.0 (2.7)a,d,c | 6.4 (3.4)a,b,d | 4.4 (2.7)b,c |
| Number of informative embryos | 3573 | 1565 | 1499 | 481 |
| Total number of aneuploid embryos (%) | 2757 (77.2) | 1248 (79.7) | 1151 (76.8) | 371 (77.1) |
| Number of segmental aneuploidies (%) | 151 (4.2) | 51 (3.2) | 56 (3.7) | 20 (4.1) |
| Number of embryos with a chaotic pattern (%) | 561 (15.7) | 250 (16.0) | 204 (13.6) | 53 (11.0) |
| Number of embryos with >1 aneuploidy (%) | 1191 (33.3) | 578 (36.9)d | 485 (32.3) | 144 (29.9)b |
| Number of embryo transfers (%) | 421 (54.4) | 156 (48.7)c | 147 (62.5)b | 59 (64.8) |
| Mean transferred embryos (SD) | 1.4 (0.5) | 1.4 (0.5) | 1.5 (0.5) | 1.5 (0.5) |
| Number of pregnancies/transfer (%) | 225 (53.4) | 93 (59.6) | 71 (48.3) | 29 (49.1) |
| Number of pregnancies/cycle (%) | 225 (29.1) | 93 (29.1) | 71 (30.2) | 29 (31.9) |
| Implantation rate | 48.1 | 51.9 | 40.0 | 43.7 |
| Miscarriage rate | 6.6 (15/225) | 8.6 (8/93) | 8.4 (6/71) | 6.9 (2/29) |
| Delivery rate/cycle | 27.1 (210) | 26.6 (85) | 27.7 (65) | 29.7 (27) |
a P < 0.05 versus fresh cycles; b P < 0.05 versus mixed vitrified oocytes; c P < 0.05 versus mixed day-2 vitrified embryos; d P < 0.05 versus mixed day-3 vitrified embryos. Chi-square test, Fisher exact test, or Welch t-test with Bonferroni's correction.