Table 4.
Chang ototoxicity scale grade level by disease risk category and amifostine treatment status
| Chang grade | Average Risk |
High Risk |
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Amifostine: No (n = 34) |
Amifostine: Yes (n = 229) |
Overall (n = 263) |
Amifostine: No (n = 17) |
Amifostine: Yes (n = 99) |
Overall (n = 116) |
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| n | % | n | % | n | % | n | % | n | % | n | % | |
| 0 | 4 | 11.8 | 95 | 41.5 | 99 | 37.6 | 5 | 29.4 | 23 | 23.2 | 28 | 24.1 |
| 1a | 7 | 20.6 | 46 | 20.1 | 53 | 20.2 | 2 | 11.8 | 14 | 14.1 | 16 | 13.8 |
| 1b | 3 | 8.8 | 14 | 6.1 | 17 | 6.5 | 1 | 5.9 | 10 | 10.1 | 11 | 9.5 |
| 2a | 2 | 5.9 | 15 | 6.6 | 17 | 6.5 | 0 | 0 | 7 | 7.1 | 7 | 6.0 |
| 2b | 4 | 11.8 | 12 | 5.2 | 16 | 6.1 | 1 | 5.9 | 7 | 7.1 | 8 | 6.9 |
| 3 | 11 | 32.4 | 43 | 18.8 | 54 | 20.5 | 7 | 41.2 | 34 | 34.3 | 41 | 35.3 |
| 4 | 3 | 8.8 | 4 | 1.8 | 7 | 2.7 | 1 | 5.9 | 4 | 4.0 | 5 | 4.3 |