Table 2.
Sensitivity analysis of PARP1 - rs1136410, XRCC1 - rs25487
| Without the Study Deviated from HWE |
||||
|---|---|---|---|---|
| Genotype/model | Ref. no. deviated from HWE | OR | 95% CI | P value* |
| PARP1 - rs1136410 | 14 | |||
| TC vs TT | 0.809 | 0.685–0.955 | .012 | |
| Dominant: TC/CC vs TT | 0.783 | 0.684–0.897 | .0004 | |
| XRCC1 - rs25487 | 37 | |||
| AG vs GG | 1.089 | 0.995–1.192 | .063 | |
| AA vs GG | 1.187 | 0.971–1.451 | .095 | |
| Dominant: GA/AA vs GG | 1.121 | 1.032–1.218 | .007 | |
| Recessive: AA vs AG/GG | 1.135 | 0.999–1.289 | .052 | |
Abbreviations: HWE, Hardy-Weinberg equilibrium; OR, odds ratio.
*Bonferroni corrected reference P values: .0015 for an experiment-wide significance of .05;.003 for a significance of .10.