Table 1.
Cellular compartment distribution of H. sapiens proteins targeted by the predicted host-pathogen PPIs
|
Cellular compartment |
Percentage(%) |
No. of |
|---|---|---|
| proteins | ||
|
(a) |
|
|
| GO:0048471 perinuclear region of cytoplasm |
12.2 |
44 |
| GO:0005730 nucleolus |
7.50 |
27 |
| GO:0005615 extracellular space |
5.56 |
20 |
| GO:0016607 nuclear speck |
5.28 |
19 |
| GO:0005813 centrosome |
3.89 |
14 |
| GO:0031965 nuclear membrane |
2.78 |
10 |
| GO:0005667 transcription factor complex |
2.78 |
10 |
| GO:0000502 proteasome complex |
2.50 |
9 |
| GO:0042470 melanosome |
2.50 |
9 |
| GO:0009897 external side of plasma membrane |
2.22 |
8 |
|
(b) |
|
|
| GO:0048471 perinuclear region of cytoplasm |
11.9 |
14 |
| GO:0043025 neuronal cell body |
5.93 |
7 |
| GO:0005730 nucleolus |
5.08 |
6 |
| GO:0005759 mitochondrial matrix |
5.08 |
6 |
| GO:0016585 chromatin remodeling complex |
4.24 |
5 |
| GO:0005813 centrosome |
3.39 |
4 |
| GO:0005667 transcription factor complex |
3.39 |
4 |
| GO:0031965 nuclear membrane |
3.39 |
4 |
| GO:0017053 transcriptional repressor complex |
2.54 |
3 |
| GO:0005741 mitochondrial outer membrane | 2.54 | 3 |
This table summarizes top 10 most frequent cellular compartments where the H. sapiens proteins (targeted by the predicted host-pathogen PPIs) likely to be located in.
(a) is cellular compartment distribution of H. sapiens proteins targeted by the stringent homology-based approach predicted host-pathogen PPIs (Top 10 cellular compartments).
(b) is cellular compartment distribution of H. sapiens proteins targeted by the conventional homology-based approach predicted host-pathogen PPIs (Top 10 cellular compartments).