Table 8.
Topological properties analysis result
| Organism | H. sapiens proteins | M. tuberculosis proteins | ||
|---|---|---|---|---|
|
PPIN |
Hum-Mtb |
Hum-Hum |
Hum-Mtb |
Mtb-Mtb |
| Average degree |
26.69 |
12.56 |
25.67 |
16.16 |
| P-value |
2.18E-11 |
7.34E-9 |
||
| Average betweeness centrality |
6.33E-4 |
8.23E-4 |
8.36E-3 |
1.63E-2 |
| P-value |
0.439 |
0.132 |
||
| Average shortest path length |
3.33 |
3.57 |
4.73 |
4.77 |
| P-value | 1.33E-30 | 0.65 | ||
This table summarizes our analysis of intra-species PPIN topological properties for H. sapiens and M. tuberculosis H37Rv proteins involved in the predicted host-pathogen PPI dataset, compared with proteins involved in intra-species PPIN.
Abbreviations: Hum-Mtb: in predicted H. sapiens–M. tuberculosis H37Rv PPIN. Hum-Hum: in H. sapiens intra-species PPIN. Mtb-Mtb: in M. tuberculosis intra-species PPIN.