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. Author manuscript; available in PMC: 2014 May 15.
Published in final edited form as: Anal Bioanal Chem. 2008 Dec 7;393(4):1135–1141. doi: 10.1007/s00216-008-2521-y

Fig. 3.

Fig. 3

Nanoprobe interrogation of single living cells. SERS-active, pH-sensitive fiber-optic nanoprobes can be quickly and easily inserted into single living cells suspended in a supporting matrix or grown on microscope slides. The approach toward a single cell (a) and insertion for laser interrogation (b) are accomplished through use of micromanipulators