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. 2014 Mar 26;2:9. doi: 10.1186/2049-2618-2-9

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Copyright © 2014 Enav et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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VirMic enriched pathways show higher association with other metabolic pathways. (A) A circle display of the pathways in the global metabolism network sorted according to network degree. Red nodes represent pathways enriched in VirMic. Black arrow indicates the pathway with the highest degree. Degree decreases in a counter-clockwise manner (gradient arrow). Red arrow represents the highest ranked pathways in which enrichment of viral pathways was detected. (B) Degree distribution of pathways enriched in viral reads (red) and pathways not enriched in viral reads (black). Dashed lines mark the means of the two distributions.