Table 4.
Clinicopathological characteristics according to EGFR mutation type
| EGFR exon 19 | EGFR exon 20 | EGFR exon 21 | EGFR negative | |
|---|---|---|---|---|
| N |
50 |
9 |
56 (L858R in 54) |
98 |
| Age |
60.40 ± 8.83 |
64.22 ± 8.04 |
66.45 ± 8.80** |
62.68 ± 11.35 |
| Sex |
M:F = 23:27 |
M:F = 4:5 |
M:F = 16:40** |
55:43 |
| PYR |
8.09 ± 14.90 |
2.72 ± 6.55 |
4.68 ± 15.25** |
14.03 ± 19.19 |
| Pathologic stage |
50 |
9 |
54* |
95 |
| 0 |
4 |
0 |
2 |
9 |
| IA |
40 |
6 |
38 |
57 |
| IB |
4 |
2 |
12 |
18 |
| IIA |
0 |
0 |
1 |
5 |
| IIB |
1 |
1 |
0 |
0 |
| IIIA |
1 |
0 |
1 |
5 |
| IIIB |
0 |
0 |
0 |
1 |
| Nodal involvement |
1 |
1 |
2 |
10 |
| Histologic invasiveness |
50 |
9 |
55† |
98 |
| AIS |
4 |
0 |
2 |
9 |
| MIA |
7 |
0 |
4 |
5 |
| IA |
39 |
9 |
49 |
84 |
| Maximal diameter |
21.294 ± 10.713 |
26.944 ± 12.692 |
22.950 ± 8.769 |
22.376 ± 12.052 |
| Solid diameter |
9.392 ± 11.754 |
16.489 ± 15.322 |
11.900 ± 10.303 |
12.559 ± 11.257 |
| TDR | 0.765 ± 0.283 | 0.592 ± 0.312 | 0.679 ± 0.296 | 0.692 ± 0.292 |
*Data for pathologic stage were unavailable for 2 patients.
†Data for histologic invasiveness were unavailable for 1 patient.
**P value < 0.05 compared with EGFR-negative patients.