Table 6.
Prevalence of biomarker mutations in previous large population studies of lung adenocarcinoma
| Molecular biomarker | Author (reference) | Frequency | Total number | Population | Remarks |
|---|---|---|---|---|---|
|
ALK
|
Paik et al.
[23] |
6.8% |
395 |
Korean |
Surgically resected |
| |
Choi et al.
[25] |
5.4% |
331 |
Korean |
Underwent FDG-PET |
| |
Koh et al.
[26] |
20.4% |
221 |
Korean |
Advanced disease |
| |
Takeuchi et al.
[31] |
3.9% |
1121 |
Japanese |
Surgically resected |
| |
Fukui et al.
[29] |
3.9% |
720 |
Japanese |
Surgically resected |
| |
Wang et al.
[32] |
8.6% |
151 |
Chinese |
Advanced disease |
| |
Rodig et al.
[30] |
5.6% |
358 |
American |
Surgically resected, partially |
| |
This study |
2.8% |
217 |
Korean |
nGGO only |
|
EGFR
|
Choi et al.
[25] |
47.1% |
331 |
Korean |
Underwent FDG-PET |
| |
Kim et al.
[46] |
43.5% |
200 |
Korean |
- |
| |
Sun et al.
[49] |
53.1% |
358 |
Korean |
- |
| |
Kosaka et al.
[47] |
49.1% |
224 |
Japanese |
Surgically resected |
| |
Uramoto et al.
[50] |
37.8% |
437 |
Japanese |
Surgically resected |
| |
Huang et al.
[45] |
38.1% |
858 |
Chinese |
- |
| |
Liam et al.
[48] |
39.5% |
812 |
Malaysian |
- |
| This study | 54.8% | 217 | Korean | nGGO only |