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Glutamine, aspartate, glutamate and GABA as a function of protein intake and tissue in phenylketonuric (PKU) mice. Two-way ANOVA, p < 0.05 for tissue, protein intake and interaction. Two-tailed t-test, *p < 0.05 for mutant vs. wild-type. Note: For GABA in CTX, GABA was also significantly decreased in mutant vs. wild-type mice. In only a single instance did lower protein result in significant correction between mutant populations (GLN in CB).
