Table 1.

Summary of tidal volume (V_T; mL ± SEM) data in baseline, hypoxia (HX), hypercapnia (HC) and hypoxia + hypercapnia (HX + HC) in all treatment groups. Groups were: Sham (WT: n=8; MT: n=9), PCPA (WT: n=3; MT: n=3), PCPA + Methy (WT: n=3; MT: n=3), MSX-3 (WT: n=3; MT: n=3), PCPA + MSX-3 (WT: n=3; MT: n=3), and Apo + MSX-3 + Methy (WT: n=3; MT: n=3). Significance was accepted at p < 0.05; 3 = Sham MT vs. treatment group MT..

Tidal Volume	Baseline	HX	HC	HX + HC
Sham WT	3.0 ±0.3	3.5 ±0.4	4.8 ±0.6	5.8 ±0.6
Sham MT	3.4 ±0.2	3.9 ±0.3	4.9 ±0.3	5.3 ±0.4
PCPA WT	3.8 ± 0.8	3.8 ± 0.5	5.1 ± 0.6	5.8 ± 1.1
PCPA MT	3.32 ± 0.04	3.7 ± 0.2	5.2 ± 0.4	5.8 ± 0.7
PCPA + Methy WT	4.3 ± 0.3	4.1 ± 0.3	7.0 ± 0.4	7.1 ± 0.4
PCPA + Methy MT	3.9 ± 0.2	3.8 ± 0.3	6.6 ± 0.1	7.0 ± 0.1
MSX-3 WT	3.4 ± 0.1	3.5 ± 0.2	4.9 ± 0.2	5.4 ± 0.1
MSX-3 MT	3.8 ± 0.2	3.9 ± 0.1	4.9 ± 0.2	5.51 ± 0.04
MSX-3 + PCPA WT	4.2 ± 0.1	4.3 ± 0.2	6.3 ± 0.2	7.0 ± 0.3
MSX-3 + PCPA MT	4.5 ± 0.2	4.1 ± 0.2	6.1 ± 0.1	6.9 ± 0.2
Apocynin + MSX-3 + Methy WT	4.1 ± 0.2	4.4 ± 0.1	6.3 ± 0.3	7.2 ± 0.7
Apocynin + MSX-3 + Methy MT	4.1 ± 0.3	4.4 ± 0.3	6.7 ± 0.4	7.6 ± 0.53