Figure 1. Cytokine production by isolated splenocytes from C57BL/6 mice immunized with recMAGE-A3 alone or formulated with different immunostimulants.

The mice were immunized on Days 0, 14, 28 and 42 with recMAGE-A3 (10 µg of antigen) alone or recMAGE-A3 formulated with different immunostimulants, and re-stimulated in vitro by bacMAGE-A3. Cytokine production was measured by cytometric bead array (CBA) after 72 h of culture. Each dot represents a mouse, and bars are geomeans. N, not done.