Table 5. Blood pressure follow-up in conscious SHHF rats.
Genotype | SHHF+/? | SHHFcp/cp | ANOVA | |||||||||
Age, month | 2.5 | 5 | 13 | 14 | 2.5 | 5 | 13 | 14 | Genotype | Age | Interaction | |
N | 8 | 8 | 7 | 7 | 9 | 9 | 6 | 5 | ||||
SBP, mmHg | 176±4 | 182±12 | 187±6 | 195±8 | 150±8 | 163±14 | 182±7 | 207±9 | ns | <0.0001 | ns | |
HR, bpm | 397±5 | 383±12 | 466±13 | 460±6 | 368±10* | 390±6 | 401±20* | 412±18* | <0.0001 | <0.0001 | 0.0020 |
SBP, Systolic Blood Pressure; HR, Heart Rate; bpm, beats per minute. Values are mean ± sem. Non-parametric ANOVAs analysis with two factors allowed the evaluation of interaction between aging and genotype. N stands for the number of rats; ns stands for not significant. Student's T test * p<0.05 to compare SHHFcp/cp vs. SHHF+/? at same age.