Table 1. Main effects of genotype (and photoperiod) on circadian behavioral phenotypes.
| Genotype | main-effects | |||||
| Characteristic | Pet-1+/+ | Pet-1+/− | Pet-1−/− | d.f. | F or Χ2 | p |
| IR Behavioral - LD | ||||||
| Onset (ZT) | 12.0±0.02 | 12.0±0.03 | 11.5±0.09 | 2 | 33.856 | <0.001 |
| OnsetError (h) | 0.18±0.01 | 0.16±0.01 | 0.30±0.03 | 2 | 17.614 | <0.001 |
| Offset (ZT) | 0.4±0.08 | 0.1±0.06 | 1.9±0.13 | 2, 75 | 2.361 | 0.101 |
| OffsetError (h) | 0.21±0.03 | 0.22±0.03 | 0.33±0.02 | 2, 75 | 0.802 | 0.452 |
| Duration (h) | 12.4±0.08 | 12.1±0.07 | 14.3±0.20 | 2 | 57.207 | <0.001 |
| Power (AU) | 1537.4±108.2 | 1588.1±94.6 | 1338.2±36.7 | 2 | 3.246 | 0.197 |
| % Light Activity | 52.0±3.78 | 46.7±1.73 | 53.6±1.08 | 2 | 14.543 | 0.001 |
| Average Activity (counts/min) | 1.41±0.25 | 1.16±0.08 | 1.16±0.06 | 2 | 0.055 | 0.973 |
| Total Activity (counts/day) | 2044.3±362.5 | 1698.5±121.5 | 1675.3±86.6 | 2 | 0.027 | 0.987 |
| Periodic Component Ratio (AU) | 0.192±0.03 | 0.138±0.02 | 0.480±0.02 | 2 | 55.128 | <0.001 |
| IR Behavioral - DD | ||||||
| Period (h) | 23.79±0.02 | 23.76±0.02 | 23.66±0.03 | 2, 75 | 7.886 | 0.001 |
| OnsetError (h) | 0.33±0.03 | 0.47±0.07 | 0.47±0.03 | 2 | 5.726 | 0.057 |
| OffsetError (h) | 0.55±0.03 | 0.53±0.04 | 0.60±0.03 | 2, 75 | 0.972 | 0.383 |
| Duration (h) | 13.0±0.30 | 13.6±0.20 | 16.3±0.20 | 2, 75 | 60.131 | <0.001 |
| Power (AU) | 1273.3±81.1 | 1315.8±90.3 | 1037.8±48.5 | 2 | 8.978 | 0.011 |
| Average Activity (counts/min) | 1.16±0.12 | 1.11±0.06 | 1.20±0.07 | 2 | 0.706 | 0.703 |
| Total Activity (counts/day) | 1661.4±178.9 | 1600.6±83.8 | 1727.3±97.0 | 2 | 0.705 | 0.703 |
| Periodic Component Ratio (AU) | 0.243±0.03 | 0.268±0.03 | 0.587±0.03 | 2,75 | 86.069 | <0.001 |
| Wheel Behavioral - LD | ||||||
| Onset (ZT) | 12.2±0.03 | 12.2±0.03 | 11.7±0.13 | 2 | 15.783 | <0.001 |
| OnsetError (h) | 0.09±0.01 | 0.10±0.01 | 0.40±0.11 | 2 | 7.521 | 0.023 |
| Offset (ZT) | 20.2±0.64 | 21.5±0.31 | 1.8±0.21 | 2, 36 | 73.379 | <0.001 |
| OffsetError (h) | 0.70±0.12 | 0.85±0.08 | 0.41±0.07 | 2, 36 | 7.915 | 0.001 |
| Duration (h) | 8.02±0.64 | 9.27±0.33 | 14.01±0.30 | 2, 36 | 70.566 | <0.001 |
| Power (AU) | 2251.3±70.7 | 2575.4±141.2 | 1589.8±120.1 | 2, 35 | 17.832 | <0.001 |
| % Light Activity | 1.47±0.28 | 0.82±0.29 | 20.10±3.82 | 2 | 25.419 | <0.001 |
| Average Activity (revs/min) | 13.0±0.88 | 16.8±1.46 | 7.5±0.91 | 2, 35 | 17.823 | <0.001 |
| Total Activity (revs/day) | 18790±1273 | 24151±2108 | 10865±1312 | 2, 35 | 17.823 | <0.001 |
| Periodic Component Ratio (AU) | 0.190±0.01 | 0.178±0.01 | 0.397±0.04 | 2 | 19.425 | <0.001 |
| Wheel Behavioral - DD | ||||||
| Period (h) | 23.78±0.05 | 23.78±0.03 | 23.65±0.04 | 2, 36 | 3.771 | 0.033 |
| OnsetError (h) | 0.48±0.20 | 0.36±0.08 | 0.58±0.07 | 2, 36 | 1.227 | 0.305 |
| OffsetError (h) | 0.53±0.07 | 1.00±0.11 | 0.58±0.09 | 2, 36 | 7.128 | 0.002 |
| Duration (h) | 9.61 1.07 | 8.58±0.43 | 15.93±0.33 | 2 | 27.74 | <0.001 |
| Power (AU) | 1961.7±153.8 | 1976.3±169.7 | 1143.0±68.0 | 2 | 16.632 | <0.001 |
| Average Activity (revs/min) | 12.1±0.96 | 13.0±1.49 | 7.2±1.02 | 2, 35 | 7.337 | 0.002 |
| Total Activity (revs/day) | 7008±3524 | 952±947 | 3341±1314 | 2 | 1.263 | 0.532 |
| Periodic Component Ratio (AU) | 0.289±0.03 | 0.252±0.01 | 0.455±0.03 | 2 | 17.922 | <0.001 |
| Ex Vivo Per1::Luc Expression | ||||||
| Period (h) | 24.23±0.07 | 24.24±0.07 | 24.50±0.07 | 2, 155 | 4.675 | 0.011 |
| Power (AU) | 1629.3±76.2 | 1655.6±74.0 | 1623.7±79.6 | 2 | 0.051 | 0.951 |
Activity monitored by infrared motion detector and wheel in LD and DD, as denoted. Ex vivo Per1::Luc expression is below. Significance is ascribed at p ≤0.05.