Table 1. Bifurcations of CES, Characteristic Domains and Criticality at 15–20 min.
HRG | EGF | ||||
Criticality Domain | Above Dynamic | Near Transit | Below Static | Near Transit | Below Static |
Range of rmsf | >0.42 | 0.21–0.42 | <0.21 | >0.16 | <0.16 |
# of mRNAs | 3269 | 9707 | 9059 | 14944 | 7091 |
Distribution:mRNA expression | Unimodal | FlattenedUnimodal | Bimodal | FlattenedUnimodal | Bimodal |
DEAB of the expression | Up | No change | No change | No change | No change |
Coherent Expression State: CES | HES1 (EQ)andHES2 (ON) | HES1 (EQ) | HES1 (EQ)andLES1 (OFF) | HES (EQ) | HES (EQ)andLES (OFF) |
Bifurcation of CES | LES2 (ON) | Onset of birth of LES1 | LES1 (OFF) | Onset of birth of LES | LES (OFF) |
State change | LES2 (ON; 15 min)→HES2 (ON; 20 min) | - | - | - | - |