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. 2014 May 15;9(5):e97775. doi: 10.1371/journal.pone.0097775

Table 3. Studies about the rate of vertical transmission when mother got infected in pregnancy.

First author Year Area Diagnostic Standards Rate* Reference
Mother Baby#
Berrebi A 1994 Toulouse Seroconversion Positive IgM, PCR or culture, clinical signs 0.17 [56]
Pratlong F 1994 Montpellier Seroconversion, high-titre IgG with IgM Positive IgM and IgA, culture 0.11 [50]
Hohlfeld P 1994 Paris Seroconversion Positive IgM, PCR or culture 0.07 [54]
Dar FK 1997 UAE High-titre IgM Positive IgM 0.38 [52]
Jenum A 1998 Norway Seroconversion Persistent IgG beyond 12 months, positive PCR or culture 0.23 [64]
Gratzl R 1998 Austria Seroconversion, high-titre IgG and IgM Persistent IgG beyond 12 months, positive PCR 0.22 [51]
Foulon W 1999 France Seroconversion Persistent IgG beyond 12 months, reappearance of IgG after therapy 0.44 [57]
Robert-Gangneux F 1999 Paris Seroconversion Persistent IgG beyond 12 months, positive PCR or culture 0.25 [59]
Naessens A 1999 America Seroconversion Persistent IgG beyond 12 months, reappearance of IgG after therapy 0.32 [57]
Lebech M 1999 Denmark Seroconversion Persistent IgG beyond 12 months, positive IgM and/or IgA 0.19 [49]
Gilbert R 2001 EUR,Austria Seroconversion Persistent IgG beyond 12 months, positive PCR or culture 0.24 [62]
Antsaklis A 2002 Athens Seroconversion Positive IgM, PCR or culture 0.19 [60]
Logar J 2002 Ljubljana High-titre IgG, high-titre IgM and/or IgA Positive IgM and IgA 0.11 [61]
Ricci M 2003 Italy Seroconversion, high-titre IgG and IgM Persistent IgG beyond 12 months 0.11 [55]
Mombro M 2003 Italy Seroconversion, positive cultures Persistent IgG beyond 12 months, reappearance of IgG after therapy, specific IgM and/or IgA 0.22 [46]
Liu J 2004 China Positive PCR, high-titre IgM Positive PCR 0.37 [15]
Di Carlo P 2005 Italy Seroconversion Persistent IgG beyond 12 months, positive PCR 0.19 [58]
Buffolano W 2005 Campania Seroconversion Persistent IgG beyond 12 months 0.34 [63]
Berrébi A 2010 Toulouse Seroconversion Persistent IgG beyond 12 months 0.17 [53]
Hotop A 2012 Germany Seroconversion Persistent IgG beyond 12 months, positive PCR 0.05 [48]
Wallon M 2013 Lyon Seroconversion, high-titre IgG and IgM Persistent IgG beyond 12 months, positive culture 0.25 [45]

Notes:# For the positive IgM/IgA results, the purity of fetal blood was ascertained or the positive results were confirmed at least 7-10 days later; * Rate stands for vertical transmission rate caused by T.gondii infection.