Table 3. Studies about the rate of vertical transmission when mother got infected in pregnancy.
First author | Year | Area | Diagnostic Standards | Rate* | Reference | |
Mother | Baby# | |||||
Berrebi A | 1994 | Toulouse | Seroconversion | Positive IgM, PCR or culture, clinical signs | 0.17 | [56] |
Pratlong F | 1994 | Montpellier | Seroconversion, high-titre IgG with IgM | Positive IgM and IgA, culture | 0.11 | [50] |
Hohlfeld P | 1994 | Paris | Seroconversion | Positive IgM, PCR or culture | 0.07 | [54] |
Dar FK | 1997 | UAE | High-titre IgM | Positive IgM | 0.38 | [52] |
Jenum A | 1998 | Norway | Seroconversion | Persistent IgG beyond 12 months, positive PCR or culture | 0.23 | [64] |
Gratzl R | 1998 | Austria | Seroconversion, high-titre IgG and IgM | Persistent IgG beyond 12 months, positive PCR | 0.22 | [51] |
Foulon W | 1999 | France | Seroconversion | Persistent IgG beyond 12 months, reappearance of IgG after therapy | 0.44 | [57] |
Robert-Gangneux F | 1999 | Paris | Seroconversion | Persistent IgG beyond 12 months, positive PCR or culture | 0.25 | [59] |
Naessens A | 1999 | America | Seroconversion | Persistent IgG beyond 12 months, reappearance of IgG after therapy | 0.32 | [57] |
Lebech M | 1999 | Denmark | Seroconversion | Persistent IgG beyond 12 months, positive IgM and/or IgA | 0.19 | [49] |
Gilbert R | 2001 | EUR,Austria | Seroconversion | Persistent IgG beyond 12 months, positive PCR or culture | 0.24 | [62] |
Antsaklis A | 2002 | Athens | Seroconversion | Positive IgM, PCR or culture | 0.19 | [60] |
Logar J | 2002 | Ljubljana | High-titre IgG, high-titre IgM and/or IgA | Positive IgM and IgA | 0.11 | [61] |
Ricci M | 2003 | Italy | Seroconversion, high-titre IgG and IgM | Persistent IgG beyond 12 months | 0.11 | [55] |
Mombro M | 2003 | Italy | Seroconversion, positive cultures | Persistent IgG beyond 12 months, reappearance of IgG after therapy, specific IgM and/or IgA | 0.22 | [46] |
Liu J | 2004 | China | Positive PCR, high-titre IgM | Positive PCR | 0.37 | [15] |
Di Carlo P | 2005 | Italy | Seroconversion | Persistent IgG beyond 12 months, positive PCR | 0.19 | [58] |
Buffolano W | 2005 | Campania | Seroconversion | Persistent IgG beyond 12 months | 0.34 | [63] |
Berrébi A | 2010 | Toulouse | Seroconversion | Persistent IgG beyond 12 months | 0.17 | [53] |
Hotop A | 2012 | Germany | Seroconversion | Persistent IgG beyond 12 months, positive PCR | 0.05 | [48] |
Wallon M | 2013 | Lyon | Seroconversion, high-titre IgG and IgM | Persistent IgG beyond 12 months, positive culture | 0.25 | [45] |
Notes:# For the positive IgM/IgA results, the purity of fetal blood was ascertained or the positive results were confirmed at least 7-10 days later; * Rate stands for vertical transmission rate caused by T.gondii infection.