Table 2.
Sensitivity, specificity, positive predictive value, and negative predictive values resulting from the comparison of different claims based ascertainment criteria of myocardial infarction events with myocardial infarction events observed in the UNC-CFAR HIV Clinical Cohort (gold standard).
| Se* (TP) | 95% CI* | Sp* (TN) | 95% CI* | PPV* (FP) | 95% CI* | NPV* (FN) | 95% CI* | |
|---|---|---|---|---|---|---|---|---|
| Medicaid Claims-based event ascertainment algorithm† n=1,063 (17 UCHCC events) | ||||||||
| - ICD-9 410.xx in 1st or 2nd position | 0.588 (10) | 0.329, 0.816 | 0.994 (1040) | 0.988, 0.998 | 0.625 (6) | 0.354, 0.848 | 0.993 (7) | 0.986, 0.997 |
| -Length of stay ≥ 3 days | ||||||||
| - ICD-9 410.xx in 1st or 2nd position | 0.588 (10) | 0.329, 0.816 | 0.993 (1039) | 0.986, 0.997 | 0.588 (7) | 0.329, 0.816 | 0.993 (7) | 0.986, 0.997 |
| -Length of stay ≥ 1 day | ||||||||
| -ICD-9 410.xx in 1st, or 2nd position | 0.647 (11) | 0.383, 0.857 | 0.988 (1034) | 0.980, 0.994 | 0.478 (12) | 0.268, 0.694 | 0.994 (6) | 0.987, 0.997 |
| -Any length of stay | ||||||||
| -ICD-9 410.xx in any position | 0.765 (13) | 0.501, 0.932 | 0.991 (1037) | 0.984, 0.996 | 0.591 (9) | 0.364, 0.793 | 0.996 (4) | 0.990, 0.999 |
| -Length of stay ≥ 3 days | ||||||||
| -ICD-9 410.xx in any position | 0.765 (13) | 0.501, 0.932 | 0.989 (1034) | 0.980, 0.994 | 0.520 (12) | 0.313, 0.64 | 0.996 (4) | 0.990, 0.999 |
| -Length of stay ≥ 1 days | ||||||||
| -ICD-9 410.xx in any position | 0.824 (14) | 0.566, 0.962 | 0.982 (1028) | 0.972, 0.999 | 0.438 (18) | 0.264, 0.623 | 0.997 (3) | 0.992, 0.999 |
| -Any length of stay |
Se: Sensitivity; Sp: Specificity; PPV: Positive Predictive Value; NPV: Negative Predictive Value; CI: Confidence Interval; TP: True Positive; TN: True Negative; FP: False Positive; FN: False Negative
Myocardial infarctions were identified in the UNC-CFAR HIV Clinical Cohort through extensive medical chart abstraction and adjudicated by health care personnel using modified WHO Monica criteria.