Figure 6. Expression of secreted GroEL2(cl) in hip1 mutant restores wild type levels of proinflammatory cytokine responses in macrophages.

Production of IL-6, IL-1β, and TNF-α by C57BL/6 bone marrow derived macrophages (BMM) 24 hours after infection with wild type, hip1 mutant, and hip1 mutant complemented with either Hip1 (comp) or GroEL2(cl). Data are shown as mean ±S.D. of one representative experiment from three independent experiments. *, P<0.05; **, P<0.01.