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S. flexneri evade colon epithelium without inflammation. (A) H&E staining of ascending and descending colon orally infected with M90T after 3 and 24 h (n=5 per group). (B) M90T-GFP in the epithelium and lamina propria of the colon 3 h after oral infection (n=3 per group). (C) CFU of M90T in the colon and cecum 1, 3, and 24 h after infection. Graphs show mean±SEM. (one-way ANOVA with Tukey post test, ***p<0.0001).
