Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Apr 21;14(2):116–122. doi: 10.4110/in.2014.14.2.116

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2014 The Korean Association of Immunologists

This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Induction of apoptosis by LPS and simvastatin. (A) Raw264.7 cells were treated with LPS and simvastatin with FTI-276, GGTI-286, Y-27632 for 14 h, and subgenomic contents were analyzed by PI staining and flow cytometry. (B) Mevalonate pathway and inhibitors used in this study. The enzymatic target steps of simvastatin (HMG-CoA reductase inhibitor), FTI-276 (farnesyl transferase inhibitor), GGTI-286 (geranylgeranyl transferase inhibitor), and Y-27632 (Rho kinase inhibitor) were displayed.