Figure 6.

Synaptic Active-Zone Maturation Is Regulated by Miniature Neurotransmission

(A and B) Representative micrographs of synaptic boutons (above) and active zones (box above, inset below) from a typical-size bouton of (A) control (CS) and (B) iGluR^MUT mutants.

(C and D) Representative micrographs of small boutons from (C) control and (D) iGluR^MUT.

(E–G) Quantification of (E) the active-zone occurrence, (F) T-bar platform size, and (G) T-bar pedestal size (n ≥ 10). Quantification data are normalized to control (F and G).

Scale is the same in (A)–(D) and in the insets of (A)–(D). Error bars indicate ±SEM. ^∗p < 0.05, ^∗ p < 0.01, ^∗∗∗p < 0.001.