FIGURE 4.
Mitochondrial Ca2+ retention capacity of TspoloxP and AlbCre;TspoloxP mitochondria; effect of Pi, arachidonic acid, PhAsO, and Cu(OP)2. A–D, liver mitochondria from TspoloxP (black symbols) or AlbCre;TspoloxP mice (red symbols) were energized with 5 mm glutamate plus 2.5 mm malate in the presence of the indicated concentrations of Pi, arachidonic acid, PhAsO, or Cu(OP)2. In B–D, the Pi concentration was 1 mm. Values are the mean ± S.D. (error bars) of at least three independent experiments performed in duplicate.