FIGURE 4.
Bloc1s5 muted affects the expression of the BLOC-1 complex transcripts. BLOC-1 subunit transcripts from adult wild type, Bloc1s5+/mu, and Bloc1s5mu/mu mice hippocampi were analyzed by quantitative RT-PCR. A box plot depicts relative mRNA content in hippocampus (A and B) and cortex (C and D). Red boxes in A and C depict results for Bloc1s5+/mu, and red boxes in B and D for Bloc1s5mu/mu, respectively. Wild type is depicted in blue in all panels. Transcripts are listed to the left of graphs in italics (n = 3 animals with determinations in duplicate; one-way analysis of variance followed by Dunnett's multiple comparisons).