Table I.
Values of the varying parameters of the one-hit multi-target model fitted to the non-trans-RM-1, siVector-RM-1 and siRelB-RM-1 cells following radiation treatment.
| Cells | D0 | Dq | N | SF2 | SER (D0) | SER (Dq) |
|---|---|---|---|---|---|---|
| Non-trans-RM-1 | 1.92 | 3.08 | 4.97 | 0.89 | ||
| siVector-RM-1 | 1.93 | 2.76 | 4.17 | 0.84 | 0.99 | 1.12 |
| siRelB-RM-1 | 1.68 | 0.60 | 1.43 | 0.43 | 1.14 | 5.13 |
si, small interfering; non-trans-RM-1 cells, non-transfected RM-1 cells; siVector-RM-1, RM-1 cells transfected with empty vector; siRelB-RM-1, pLentilox-sh-RelB-transfected RM-1 cells; D0, mean lethal dose (Gy); Dq, dose quasithreshold (Gy); N, N-value; SF2, 2 Gy survival fraction; SER, sensitization enhancement ratio.